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Sensitive Skin? Try Retinyl Palmitate Instead of Retinol

Kaye's Beauty

In the world of anti-aging skincare, many treatments can feel intense. Retinol, for instance, requires an adjustment period with peeling, while injectables and laser treatments demand time and money. Surgical options? Those exist too, promising dramatic results.

While all approaches have their place, it’s refreshing to know that gentler alternatives, like retinyl palmitate, can help kick-start the process.

If it sounds similar to retinol, you're not wrong. Retinol is one of four common retinoids—alongside retinoic acid, retinaldehyde, and retinyl palmitate. Though they share a foundation, each works differently, and for sensitive skin, retinyl palmitate is often the most tolerable choice.


Retinyl Palmitate

TYPE: Gentle Exfoliator

KEY BENEFITS: Boosts cell turnover, evens skin tone, unclogs pores, and strengthens the dermis to slow wrinkle formation.

WHO SHOULD USE IT: As the mildest retinoid, it suits most skin types, especially those looking to maintain clear, youthful skin. However, extremely sensitive skin may still experience irritation.

USAGE: Start gradually to allow your skin to adjust, but it can be used daily over time.

BEST PAIRED WITH: Works well with antioxidants like vitamins C, E, and ferulic acid. Always pair with sunscreen, as it increases sun sensitivity.

AVOID WITH: Skip other exfoliants like glycolic or salicylic acid, abrasive scrubs, and drying toners or astringents, especially if your skin is highly sensitive.


To know more on skincare ingredients shop our skincare ingredients dictionary on Amazon. Click here to shop.


What Is Retinyl Palmitate?

Retinyl palmitate is a milder form of vitamin A commonly used in skincare. Like other retinoids, it speeds up cell turnover, smooths skin texture, and boosts collagen production to reduce wrinkles.

At one end of the retinoid spectrum is prescription-strength retinoic acid, known for its potency but also high irritation potential. On the other end is retinyl palmitate, the gentlest option, making it ideal for those with sensitive skin. While less potent, it’s easier to tolerate and can be used consistently.


Benefits for Skin

  • Speeds up cell turnover – Promotes new skin growth for a smoother texture.

  • Brightens complexion – Reduces discoloration and evens skin tone.

  • Fights wrinkles – Helps preserve collagen and thickens the skin to slow signs of aging.

  • Provides antioxidant protection – Shields skin from environmental stressors.

  • Keeps pores clear – Aids in exfoliation to prevent breakouts.

  • Easily absorbed – Works well in over-the-counter formulations.


Retinyl Palmitate vs. Other Retinoids

Retinoic acid is the only form directly usable by the skin, while retinyl palmitate must first be converted. This conversion process makes it the least intense but also the most tolerable. If quick results are a priority, stronger retinoids may be better, but for beginners or those with sensitive skin, retinyl palmitate is the gentler choice.


Possible Side Effects

Although mild, side effects can include dryness, redness, itching, or peeling, especially in sensitive skin.


How to Use It

  • Nighttime application – Retinoids degrade in sunlight and increase sun sensitivity, so use them at night.

  • Start slow – Apply every other night at first, gradually increasing to daily use.

  • Pair with a moisturizer – A basic, non-irritating moisturizer can help minimize dryness.

  • Always use SPF – Protect your skin with broad-spectrum sunscreen during the day.

Retinyl palmitate offers a beginner-friendly way to incorporate retinoids into your routine without the harsh side effects of stronger options.


The Best Products with Retinyl Palmitate

Derma E Anti-wrinkle Renewal Cream
Derma E Anti-wrinkle Renewal Cream

Along with retinyl palmitate, it contains vitamin E, allantoin, and panthenol to deeply hydrate and nourish the skin. Click here to buy.


Murad Essential-C Day Moisture
Murad Essential-C Day Moisture

This product helps repair existing photodamage while strengthening the skin against future damage. It also minimizes fine lines and wrinkles. With its multitasking formula, it can be used on the face, neck, and chest. Enriched with vitamins C and E, it provides antioxidant benefits that complement retinyl palmitate. Click here to buy.

Advanced Ceramide Capsules Daily Youth Restoring Serum
Advanced Ceramide Capsules Daily Youth Restoring Serum

Combining retinyl palmitate with ceramides, which support a healthy skin barrier, can help reduce irritation. The pre-measured capsules simplify application and are perfect for travel. Click here to buy.



Kaye's Beauty Book is here to help you choose better products that suit your skin, hair and lifestyle. All of the products mentioned are carefully researched and selected to ensure that the most credible information comes to you. If you do buy a product from one of our links, Kaye's Beauty Book may earn a commission.


II DISCLAIMER: Every skin is different, not everything works for everybody. I recommend you test the product before completely using any new product. II

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